Ozempic and similar medications like Wegovy and Mounjaro were developed to treat Type 2 diabetes, but they’ve quickly become well known for their dramatic weight loss results. This class of drugs are known as GLP-1 receptor agonists, and they work by mimicking a gut hormone that regulates appetite, leading to reduced food intake and weight loss. As their popularity rises, a new question is emerging: how do these medications affect mental health?
Potential Mental Health Concerns
While GLP-1 receptor agonists offer effective treatment for diabetes and weight loss, there are growing concerns related to potential side effects. These drugs can impact the brain’s reward pathways. The effect on appetite and cravings changes the emotions connected with food, including comfort eating, which is a common coping mechanism. Without these soothing benefits related to food, some people experience intense emotions without an affective coping strategy. Additionally, the rapid change in physical appearance after weight loss can lead to body image dysphoria and other emotional challenges, especially for individuals with a history of disordered eating or body dysmorphia.
Additionally, some patients have described side effects from the medications themselves, including feeling emotionally flat, disconnected from themselves, or depressed. There have been isolated reports of suicidal ideation, prompting investigations by regulatory bodies. While current clinical trials have not conclusively linked GLP-1 medications to mental health risks, the absence of long-term data is a critical gap.
Who Is at Risk for Mental & Emotional Health Complications?
Anyone may develop mental health concerns when utilizing GLP-1 receptor agonists. However, this is significantly more likely for those:
Who have a history of eating disorders.
With pre-existing anxiety or depression.
Adolescents and young adults (using these medications off-label).
Experiencing extreme or rapid weight loss.
Mental Health Benefits
While mental health concerns tend to steal focus, there are also mental health benefits for those using GLP-1 receptor agonists. Patients who utilize GLP-1 drugs also report increased self-confidence. These medications may lead to improved relationships with food for those with disordered eating habits like binge-eating disorders. Still others feel they have greater control of their bodies and stability after struggling with weight and diet.
Consider Therapy Alongside GLP-1 Medications
For those considering GLP-1 medications, it may be beneficial to discuss potential risks with a therapist and schedule therapy sessions before and after usage to improve the results and minimize any mental and emotional health concerns. Weight loss can be transformative, but your mental wellbeing deserves equal attention. If you want to learn more, we hope you’ll consider contacting the Lotus Psychology Group team over the phone at (248) 957-8973, via email at info@lotuspsychgroup.com, or by filling out the online request form.